BDBM19422 4-(acetylamino)-N-(2-amino-phenyl) benzamide::CI-994::N-(2-aminophenyl)-4-acetamidobenzamide::N-acetyldinaline::US11207431, Example F::US11377423, CI-994
SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1ccccc1N
InChI Key InChIKey=VAZAPHZUAVEOMC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 19422
Affinity DataKi: 223nM ΔG°: -9.07kcal/mole IC50: 147nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Fluor de Lys green as substrate by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant HDAC2 using Fluor de Lys-Green as substrate preincubated for 5 mins followed by substrate addition and measured after...More data for this Ligand-Target Pair
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of HDAC2 (unknown origin) by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of human recombinant His-tagged HDAC2 (1 to 582 residues) expressed in baculovirus infected insect cells using FLUOR DE LYS Green as subst...More data for this Ligand-Target Pair
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of recombinant human HDAC2 assessed as decrease in deacetylation of FLUOR DE LYS Green substrate preincubated for 10 mins followed by subs...More data for this Ligand-Target Pair
Affinity DataIC50: 147nMAssay Description:Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC2 expressed in Sf9 insect cells using FAM-labeled acetylated peptide A as subs...More data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of recombinant human full-length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-Ac)...More data for this Ligand-Target Pair
Affinity DataIC50: 147nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair